Human GAN (Gigaxonin) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015455)

Human GAN (Gigaxonin) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015455)

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STJE0015455
€605.63 - €833.13
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.055ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This GAN Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: GAN
Gene ID: 8139
Uniprot ID: GAN_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Expressed in brain, heart and muscle.
Post Translational Modifications Ubiquitinated by E3 ubiquitin ligase complex formed by CUL3 and RBX1 and probably targeted for proteasome-independent degradation.
Function Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival.
Protein Name Gigaxonin
Kelch-Like Protein 16
Database Links Reactome: R-HSA-8951664
Reactome: R-HSA-983168
Cellular Localisation Cytoplasm
Cytoskeleton
Alternative ELISA Names Gigaxonin ELISA kit
Kelch-Like Protein 16 ELISA kit
GAN ELISA kit
GAN1 ELISA kit
KLHL16 ELISA kit
output

Information sourced from Uniprot.org

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