| Host: |
Goat/Rabbit |
| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
This GAL1 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Conjugation: |
Unconjugated/Biotin |
| Formulation: |
Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Purification: |
Capture Purification: Antigen Affinity.Detection Purification: Protein A or G. |
| Concentration: |
0.5 mg/mL |
| Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Determination Method: |
Colormetric |
| Gene Symbol: |
LGALS1 |
| Gene ID: |
3956 |
| Uniprot ID: |
LEG1_HUMAN |
| Immunogen: |
Capture immunogen: Recombinant Human GAL1 protien.Detection Immunogen: Recombinant Human GAL1 protien. |
| Sample Type: |
Serum, plasma and other biological fluids |
| Function | Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69. |
| Protein Name | Galectin-1Gal-114 Kda Laminin-Binding ProteinHlbp1414 Kda LectinBeta-Galactoside-Binding Lectin L-14-IGalaptinHblHplLactose-Binding Lectin 1Lectin Galactoside-Binding Soluble 1Putative Mapk-Activating Protein Pm12S-Lac Lectin 1 |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixCytoplasmCan Be SecretedThe Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion |
| Alternative Antibody Pair Names | Galectin-1 antibody pairGal-1 antibody pair14 Kda Laminin-Binding Protein antibody pairHlbp14 antibody pair14 Kda Lectin antibody pairBeta-Galactoside-Binding Lectin L-14-I antibody pairGalaptin antibody pairHbl antibody pairHpl antibody pairLactose-Binding Lectin 1 antibody pairLectin Galactoside-Binding Soluble 1 antibody pairPutative Mapk-Activating Protein Pm12 antibody pairS-Lac Lectin 1 antibody pairLGALS1 antibody pair |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
