Human G3BP2 protein (Recombinant) (His-Tag) (STJP017467)

SKU:
STJP017467
£134.50 - £738.50
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human G3BP2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 30% Glycerol, 0.2M NaCl, 2mM DTT, 0.1mM PMSF
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: G3BP2
Gene ID: 9908
Uniprot ID: G3BP2_HUMAN
Immunogen Region: 1-449aa
Accession Number: NP_987100.1
Immunogen: Human
Immunogen Sequence: MVMEKP SPLLVGREFV RQYYTLLNKA PEYLHRFYGR NSSYVHGGVD ASGKPQEAVY GQNDIHHKVL SLNFSECHTK IRHVDAHATL SDGVVVQVMG LLSNSGQPER KFMQTFVLAP EGSVPNKFYV HNDMFRYEDE VFGDSEPELD EESEDEVEEE QEERQPSPEP VQENANSGYY EAHPVTNGIE EPLEESSHEP EPEPES
Post Translational Modifications (Microbial infection) Cleaved by foot-and-mouth disease virus leader protease.this cleavage suppresses the formation of cytoplasmic stress granules.
Function Scaffold protein that plays an essential role in cytoplasmic stress granule formation which acts as a platform for antiviral signaling. Plays an essential role in stress granule formation. Stress granules are membraneless compartments that store mRNAs and proteins, such as stalled translation pre-initiation complexes, in response to stress. Promotes formation of stress granules phase-separated membraneless compartment by undergoing liquid-liquid phase separation (LLPS) upon unfolded RNA-binding: functions as a molecular switch that triggers RNA-dependent LLPS in response to a rise in intracellular free RNA concentrations.
Protein Name Ras Gtpase-Activating Protein-Binding Protein 2
G3bp-2
Gap Sh3 Domain-Binding Protein 2
Database Links Reactome: R-HSA-9705671
Cellular Localisation Cytoplasm
Stress Granule
Alternative Protein Names Ras Gtpase-Activating Protein-Binding Protein 2 protein
G3bp-2 protein
Gap Sh3 Domain-Binding Protein 2 protein
G3BP2 protein
KIAA0660 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP019690 Human IRF2 protein (Recombinant) (His-Tag) (STJP019690) E.coli SDS-PAGE
STJP017768 Human CSTF1 protein (Recombinant) (His-Tag) (STJP017768) E.coli SDS-PAGE/Denatured
STJP017869 Human RNF4 protein (Recombinant) (His-Tag) (STJP017869) E.coli SDS-PAGE
STJP017870 Human NDUFA5 protein (Recombinant) (His-Tag) (STJP017870) E.coli SDS-PAGE
STJP017883 Human NDUFAF1 protein (Recombinant) (His-Tag) (STJP017883) E.coli SDS-PAGE

Related Products

!