| Host: |
HEK293 cells |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: |
Lyophilised from a 0.2 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: |
< 0.01 EU/Mu g of the protein by LAL method. |
| Immunoreactivity: |
Measured by its ability to neutralize Activin-mediated erythroid differentiation of K562 human chronic myelogenous leukemia cells. The ED50 for this effect is 0.1-0.4 Mu g/mL in the presence of 7.5 ng/mL of rhActivin A. |
| Gene Symbol: |
FST |
| Gene ID: |
10468 |
| Uniprot ID: |
FST_HUMAN |
| Immunogen Region: |
Gly30-Asn317 |
| Immunogen: |
Recombinant Human Follistatin/Follistatin 288/FST Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly30-Asn317) of human Follistatin/Follistatin 288/FST (Accession #P19883) with a hFC at the N-ter |
| Immunogen Sequence: |
GNCWLRQAKNGRCQVLYKTE LSKEECCSTGRLSTSWTEED VNDNTLFKWMIFNGGAPNCI PCKETCENVDCGPGKKCRMN KKNKPRCVCAPDCSNITWKG PVCGLDGKTYRNECALLKAR CKEQPELEVQYQGRCKKTCR DVFCPGSSTCVVDQTNNAYC VTCNRICPEPASSEQYLCGN DGVTYSSACHLRKATCLLGR SIGLAYEGKCIKAKSCEDIQ CTGGKKCLWDFKVGRGRCS |
| Function | Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). |
| Protein Name | FollistatinFsActivin-Binding Protein |
| Database Links | Reactome: R-HSA-2473224 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Follistatin proteinFs proteinActivin-Binding Protein proteinFST protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
