Human FNDC5 protein (Recombinant) (N-His) (STJP005708)

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STJP005708
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Short Description :Recombinant-Human FNDC5-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution.
Formulation:Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:FNDC5
Gene ID:252995
Uniprot ID:FNDC5_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Met76-Lys211
Post Translational Modifications The extracellular domain is cleaved and released from the cell membrane. N-Glycosylated.
Function Irisin: Mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA.
Protein Name Fibronectin Type Iii Domain-Containing Protein 5
Fibronectin Type Iii Repeat-Containing Protein 2 Cleaved Into - Irisin
Database Links
Cellular Localisation Fibronectin Type Iii Domain-Containing Protein 5: Cell Membrane
Single-Pass Membrane Protein
Peroxisome Membrane
Imported Into Peroxisomes Through The Pex5 Receptor Pathway
Irisin: Secreted
Detected In Plasma Following Endurance Exercise
Alternative Protein Names Fibronectin Type Iii Domain-Containing Protein 5 protein
Fibronectin Type Iii Repeat-Containing Protein 2 Cleaved Into - Irisin protein
FNDC5 protein
FRCP2 protein

Information sourced from Uniprot.org

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