Human FHL2 protein (Recombinant) (His-Tag) (STJP018950)

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STJP018950
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Host: E.coli
Applications: SDS-PAGE/Denatured
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FHL2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol
Concentration: 0.5 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: FHL2
Gene ID: 2274
Uniprot ID: FHL2_HUMAN
Immunogen Region: 1-279aa
Accession Number: NP_001034581
Immunogen: Human
Immunogen Sequence: MTERFDC HHCNESLFGK KYILREESPY CVVCFETLFA NTCEECGKPI GCDCKDLSYK DRHWHEACFH CSQCRNSLVD KPFAAKEDQL LCTDCYSNEY SSKCQECKKT IMPGTRKMEY KGSSWHETCF ICHRCQQPIG TKSFIPKDNQ NFCVPCYEKQ HAMQCVQCKK PITTGGVTYR EQPWHKECFV CTACRKQLSG QRFTAR
Tissue Specificity Expressed in skeletal muscle and heart.
Function May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Negatively regulates the calcineurin/NFAT signaling pathway in cardiomyocytes.
Protein Name Four And A Half Lim Domains Protein 2
Fhl-2
Lim Domain Protein Dral
Skeletal Muscle Lim-Protein 3
Slim-3
Database Links Reactome: R-HSA-1989781
Cellular Localisation Cytoplasm
Nucleus
Myofibril
Sarcomere
Z Line
Alternative Protein Names Four And A Half Lim Domains Protein 2 protein
Fhl-2 protein
Lim Domain Protein Dral protein
Skeletal Muscle Lim-Protein 3 protein
Slim-3 protein
FHL2 protein
DRAL protein
SLIM3 protein

Information sourced from Uniprot.org

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