• Human FGF-19 protein (Recombinant) (C-His) (STJP001244)
  • Human FGF-19 protein (Recombinant) (C-His) (STJP001244)
  • Human FGF-19 protein (Recombinant) (C-His) (STJP001244)
  • Human FGF-19 protein (Recombinant) (C-His) (STJP001244)

Human FGF-19 protein (Recombinant) (C-His) (STJP001244)

SKU:
STJP001244

£63.50 - £189.50
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human FGF-19-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human FGF19 at 5 Mu g/mL (100 Mu L/well) can bind Recombinant Human FGFR4 with a linear range of 0.9-3.8 Mu g/mL.
Gene Symbol: FGF19
Gene ID: 9965
Uniprot ID: FGF19_HUMAN
Immunogen Region: Phe27-Lys216
Immunogen: Recombinant Human FGF-19 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Phe27-Lys216) of human FGF-19 (Accession #NP_005108.1) fused with a 6×His tag at the C-terminus.
Tissue Specificity Expressed in fetal brain, cartilage, retina, and adult gall bladder.
Function Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
Protein Name Fibroblast Growth Factor 19
Fgf-19
Database Links Reactome: R-HSA-109704
Reactome: R-HSA-1257604
Reactome: R-HSA-1307965
Reactome: R-HSA-190322
Reactome: R-HSA-2219530
Reactome: R-HSA-5654228
Reactome: R-HSA-5654712
Reactome: R-HSA-5654719
Reactome: R-HSA-5654720
Reactome: R-HSA-5654733
Reactome: R-HSA-5673001
Reactome: R-HSA-6811558
Cellular Localisation Secreted
Alternative Protein Names Fibroblast Growth Factor 19 protein
Fgf-19 protein
FGF19 protein
UNQ334 protein
PRO533 protein

Information sourced from Uniprot.org

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