Human FGD5 protein (Recombinant) (N-His) (STJP009657)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human FGD5-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | FGD5 |
| Gene ID | 152273 |
| Uniprot ID | FGD5_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Arg892-Arg1035 |
Additional Info
| Function | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape. |
| Protein Name | Fyve - Rhogef And Ph Domain-Containing Protein 5Zinc Finger Fyve Domain-Containing Protein 23 |
| Database Links | Reactome: R-HSA-9013149 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionRuffle MembraneEndoplasmic ReticulumGolgi ApparatusEarly EndosomeIn Peripheral Membrane RufflesColocalizes With F-ActinIn Confluent HuvecsDetected At Cell-Cell-Contact Sites Where It Colocalizes With Vascular Endothelial Cadherin/Cdh5 |
| Alternative Protein Names | Fyve - Rhogef And Ph Domain-Containing Protein 5 proteinZinc Finger Fyve Domain-Containing Protein 23 proteinFGD5 proteinZFYVE23 protein |
Information sourced from Uniprot.org