Human FGD5 protein (Recombinant) (N-His) (STJP009657)

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STJP009657
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FGD5-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: FGD5
Gene ID: 152273
Uniprot ID: FGD5_HUMAN
Immunogen Region: Arg892-Arg1035
Immunogen: Homo sapiens (Human)
Function Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.
Protein Name Fyve - Rhogef And Ph Domain-Containing Protein 5
Zinc Finger Fyve Domain-Containing Protein 23
Database Links Reactome: R-HSA-9013149
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Projection
Ruffle Membrane
Endoplasmic Reticulum
Golgi Apparatus
Early Endosome
In Peripheral Membrane Ruffles
Colocolizes With F-Actin
In Confluent Huvecs
Detected At Cell-Cell-Contact Sites Where It Colocalizes With Vascular Endothelial Cadherin/Cdh5
Alternative Protein Names Fyve - Rhogef And Ph Domain-Containing Protein 5 protein
Zinc Finger Fyve Domain-Containing Protein 23 protein
FGD5 protein
ZFYVE23 protein

Information sourced from Uniprot.org

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