Human Ferritin heavy chain 1/FTH1 protein (Recombinant) (No-Tag) (STJP019627)

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STJP019627
£134.50 - £738.50
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human Ferritin heavy chain 1/FTH1-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 7.5) containing, 10% Glycerol, 1mM DTT
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: FTH1
Gene ID: 2495
Uniprot ID: FRIH_HUMAN
Immunogen Region: 1-183aa
Accession Number: NP_002023.2
Immunogen: Human
Immunogen Sequence: MTTASTSQVR QNYHQDSEAA INRQINLELY ASYVYLSMSY YFDRDDVALK NFAKYFLHQS HEEREHAEKL MKLQNQRGGR IFLQDIKKPD CDDWESGLNA MECALHLEKN VNQSLLELHK LATDKNDPHL CDFIETHYLN EQVKAIKELG DHVTNLRKMG APESGLAEYL FDKHTLGDSD NES
Tissue Specificity Expressed in the liver.
Function Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron.
Protein Name Ferritin Heavy Chain
Ferritin H Subunit
Cell Proliferation-Inducing Gene 15 Protein Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed
Database Links Reactome: R-HSA-3000480
Reactome: R-HSA-432722
Reactome: R-HSA-6798695
Reactome: R-HSA-917937
Cellular Localisation Cytoplasm
Lysosome
Cytoplasmic Vesicle
Autophagosome
Alternative Protein Names Ferritin Heavy Chain protein
Ferritin H Subunit protein
Cell Proliferation-Inducing Gene 15 Protein Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed protein
FTH1 protein
FTH protein
FTHL6 protein
OK protein
SW-cl.84 protein
PIG15 protein

Information sourced from Uniprot.org

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