Human FCN1 protein (Recombinant) (N-His) (STJP009034)

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STJP009034
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Short Description :Recombinant-Human FCN1-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:FCN1
Gene ID:2219
Uniprot ID:FCN1_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Gly130-Ala326
Function Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.
Protein Name Ficolin-1
Collagen/Fibrinogen Domain-Containing Protein 1
Ficolin-A
Ficolin-Alpha
M-Ficolin
Database Links Reactome: R-HSA-166662
Reactome: R-HSA-166663
Reactome: R-HSA-2855086
Reactome: R-HSA-6798695
Cellular Localisation Secreted
Cell Membrane
Peripheral Membrane Protein
Extracellular Side
Found On The Monocyte And Granulocyte Surface
Alternative Protein Names Ficolin-1 protein
Collagen/Fibrinogen Domain-Containing Protein 1 protein
Ficolin-A protein
Ficolin-Alpha protein
M-Ficolin protein
FCN1 protein
FCNM protein

Information sourced from Uniprot.org