| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 15.25pg/mL |
| Detection Limit: | 46.8-3000pg/mL |
| Short Description: | This FcgRII Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma or other biological fluids.. |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | FCGR2A |
| Gene ID: | 2212 |
| Uniprot ID: | FCG2A_HUMAN |
| Sample Type: | serum, plasma or other biological fluids. |
| Tissue Specificity | Found on monocytes, neutrophils and eosinophil platelets. |
| Post Translational Modifications | Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK. |
| Function | Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. |
| Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A Igg Fc Receptor Ii-A Cdw32 Fc-Gamma Rii-A Fc-Gamma-Riia Fcrii-A Cd Antigen Cd32 |
| Database Links | Reactome: R-HSA-2029481 Reactome: R-HSA-2029482 Reactome: R-HSA-2029485 Reactome: R-HSA-6798695 Reactome: R-HSA-9664323 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
| Alternative ELISA Names | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A ELISA kit Igg Fc Receptor Ii-A ELISA kit Cdw32 ELISA kit Fc-Gamma Rii-A ELISA kit Fc-Gamma-Riia ELISA kit Fcrii-A ELISA kit Cd Antigen Cd32 ELISA kit FCGR2A ELISA kit CD32 ELISA kit FCG2 ELISA kit FCGR2A1 ELISA kit IGFR2 ELISA kit |
| output |
Information sourced from Uniprot.org
