Human FcgRII (Receptor II For The Fc Region Of Immunoglobulin G) Sandwich ELISA Kit (STJE0008831)
SPECIFICATIONS
General Information
| Short Description | This FcgRII Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 15.25pg/mL |
| Detection Limit | 46.8-3000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | FCGR2A |
| Gene ID | 2212 |
| Uniprot ID | FCG2A_HUMAN |
| Sample Type | serum, plasma or other biological fluids. |
Additional Info
| Tissue Specificity | Found on monocytes, neutrophils and eosinophil platelets. |
| Post Translational Modifications | Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK. |
| Function | Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. |
| Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-AIgg Fc Receptor Ii-ACdw32Fc-Gamma Rii-AFc-Gamma-RiiaFcrii-ACd Antigen Cd32 |
| Database Links | Reactome: R-HSA-2029481Reactome: R-HSA-2029482Reactome: R-HSA-2029485Reactome: R-HSA-6798695Reactome: R-HSA-9664323 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative ELISA Names | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A ELISA kitIgg Fc Receptor Ii-A ELISA kitCdw32 ELISA kitFc-Gamma Rii-A ELISA kitFc-Gamma-Riia ELISA kitFcrii-A ELISA kitCd Antigen Cd32 ELISA kitFCGR2A ELISA kitCD32 ELISA kitFCG2 ELISA kitFCGR2A1 ELISA kitIGFR2 ELISA kit |
| output |
Information sourced from Uniprot.org