Name: Human FCER1A protein (Recombinant-Active) (C-His) (STJP011860)
SKU: STJP011860-100
Price: 747.23 USD
Availability: InStock

Human FCER1A protein (Recombinant-Active) (C-His) (STJP011860)

SKU:

STJP011860-100

$747.23

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Host:	Mammalian Cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Active-Human FCER1A-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range:	Reconstitute in sterile water for a stock solution.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:	<0.1 EU/Mu g of the protein by the LAL method.

Function	High-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells. Upon IgE binding and antigen/allergen cross-linking initiates signaling pathways that lead to myeloid cell activation and differentiation. On mast cells, basophils and eosinophils stimulates the secretion of vasoactive amines, lipid mediators and cytokines that contribute to inflammatory response, tissue remodeling and cytotoxicity against microbes. Triggers the immediate hypersensitivity response to allergens as a host defense mechanism against helminth parasites, pathogenic bacteria and venom toxicity. When dysregulated, it can elicit harmful life-threatening allergic and anaphylactic reactions.
Protein Name	High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha Fc-Epsilon Ri-Alpha Fceri Ige Fc Receptor Subunit Alpha
Database Links	Reactome: R-HSA-2454202 Reactome: R-HSA-2730905 Reactome: R-HSA-2871796 Reactome: R-HSA-2871809 Reactome: R-HSA-2871837
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha protein Fc-Epsilon Ri-Alpha protein Fceri protein Ige Fc Receptor Subunit Alpha protein FCER1A protein FCE1A protein

Information sourced from Uniprot.org

Model	Name	Host
STJP008186	Human FCER1A protein (Recombinant) (N-His) (STJP008186)	E. coli
STJP011882	Human CD46 protein (Recombinant-Active) (C-His) (STJP011882)	Mammalian Cells
STJP011880	Human FOLR1 protein (Recombinant-Active) (C-His) (STJP011880)	Mammalian Cells
STJP011906	Human KLK2 protein (Recombinant-Active) (C-His) (STJP011906)	Mammalian Cells
STJP011925	Human ACHE protein (Recombinant-Active) (C-His) (STJP011925)	Mammalian Cells

Human FCER1A protein (Recombinant-Active) (C-His) (STJP011860)