• Biotinylated Human Fc gamma RI on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
  • The purity of Biotinylated Human Fc gamma RI is greater than 95% as determined by SEC-HPLC.
  • Biotinylated Human Fc gamma RI, His-Avi Tag captured on CM5 Chip via Anti-His Antibody can bind Trastuzumab with an affinity constant of 0. 91 nM as determined in SPR assay (Biacore T200).

Human Fc gamma RI/CD64 protein (Recombinant) (C-His-Avi) {Biotin} (STJP001754)

SKU:
STJP001754

£618.50 - £1,909.50
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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Fc gamma RI/CD64-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: FCGR1A
Gene ID: 2209
Uniprot ID: FCGR1_HUMAN
Immunogen Region: Gln16-Pro288
Immunogen: DNA sequence encoding Human Fc gamma RI/CD64 including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Post Translational Modifications Phosphorylated on serine residues.
Function High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells.
Protein Name High Affinity Immunoglobulin Gamma Fc Receptor I
Igg Fc Receptor I
Fc-Gamma Ri
Fcri
Fc-Gamma Ria
Fcgammaria
Cd Antigen Cd64
Database Links Reactome: R-HSA-1236978
Reactome: R-HSA-198933
Reactome: R-HSA-2029481
Reactome: R-HSA-2029482
Reactome: R-HSA-2029485
Reactome: R-HSA-877300
Reactome: R-HSA-9664323
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Stabilized At The Cell Membrane Through Interaction With Fcer1g
Alternative Protein Names High Affinity Immunoglobulin Gamma Fc Receptor I protein
Igg Fc Receptor I protein
Fc-Gamma Ri protein
Fcri protein
Fc-Gamma Ria protein
Fcgammaria protein
Cd Antigen Cd64 protein
FCGR1A protein
FCG1 protein
FCGR1 protein
IGFR1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance