Human FAM132A (Family With Sequence Similarity 132, Member A) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015156)

Human FAM132A (Family With Sequence Similarity 132, Member A) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015156)

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STJE0015156
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.058ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This FAM132A Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: C1qtnf12
Gene ID: 67389
Uniprot ID: ADIPL_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Widely expressed, with high expression in subcutaneous and epididymal white adipose tissues and brown adipose tissue. Expressed in adipocytes (at protein level).
Post Translational Modifications Processed into Adipolin fC1QTNF12 and Adipolin gC1QTNF12 by FURIN. Insulin enhances endogenous C1QTNF12 cleavage.
Function Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue. Adipolin fC1QTNF12: Acts by activating the Akt signaling in hepatocytes and adipocytes. Not able to increase insulin-stimulated glucose uptake in adipocytes. Adipolin gC1QTNF12: Acts by activating the MAP kinase. Increases insulin-stimulated glucose uptake in adipocytes.
Protein Name Adipolin
Adipose-Derived Insulin-Sensitizing Factor
Complement C1q Tumor Necrosis Factor-Related Protein 12 Cleaved Into - Adipolin Fc1qtnf12
Adipolin Fctrp12
Adipolin Full-Length Form - Adipolin Gc1qtnf12
Adipolin Cleaved Form
Adipolin Gctrp12
Database Links
Cellular Localisation Adipolin Fc1qtnf12: Secreted
Adipolin Gc1qtnf12: Secreted
In Serum Is The Predominant Form
Alternative ELISA Names Adipolin ELISA kit
Adipose-Derived Insulin-Sensitizing Factor ELISA kit
Complement C1q Tumor Necrosis Factor-Related Protein 12 Cleaved Into - Adipolin Fc1qtnf12 ELISA kit
Adipolin Fctrp12 ELISA kit
Adipolin Full-Length Form - Adipolin Gc1qtnf12 ELISA kit
Adipolin Cleaved Form ELISA kit
Adipolin Gctrp12 ELISA kit
C1qtnf12 ELISA kit
C1qdc2 ELISA kit
Ctrp12 ELISA kit
Fam132a ELISA kit
output

Information sourced from Uniprot.org

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