Human ERAP2 protein (Recombinant) (N-His) (STJP005584)

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STJP005584
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ERAP2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ERAP2
Gene ID: 64167
Uniprot ID: ERAP2_HUMAN
Immunogen Region: Pro41-Phe271
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated.
Function Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys.
Protein Name Endoplasmic Reticulum Aminopeptidase 2
Leukocyte-Derived Arginine Aminopeptidase
L-Rap
Database Links Reactome: R-HSA-983170
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Endoplasmic Reticulum Aminopeptidase 2 protein
Leukocyte-Derived Arginine Aminopeptidase protein
L-Rap protein
ERAP2 protein
LRAP protein

Information sourced from Uniprot.org

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