Human EAAT2 (Excitatory Amino Acid Transporter 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014929)

Human EAAT2 (Excitatory Amino Acid Transporter 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014929)

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STJE0014929
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.113ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This EAAT2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: SLC1A2
Gene ID: 6506
Uniprot ID: EAA2_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Glycosylated. Palmitoylation at Cys-38 is not required for correct subcellular localization, but is important for glutamate uptake activity.
Function Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport.this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate.
Protein Name Excitatory Amino Acid Transporter 2
Glutamate/Aspartate Transporter Ii
Sodium-Dependent Glutamate/Aspartate Transporter 2
Solute Carrier Family 1 Member 2
Database Links Reactome: R-HSA-210455
Reactome: R-HSA-210500
Reactome: R-HSA-425393
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative ELISA Names Excitatory Amino Acid Transporter 2 ELISA kit
Glutamate/Aspartate Transporter Ii ELISA kit
Sodium-Dependent Glutamate/Aspartate Transporter 2 ELISA kit
Solute Carrier Family 1 Member 2 ELISA kit
SLC1A2 ELISA kit
EAAT2 ELISA kit
GLT1 ELISA kit
output

Information sourced from Uniprot.org

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