Human DYNLRB1 protein (Recombinant) (His-Tag) (STJP016794)

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STJP016794
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Short Description :Recombinant-Human DYNLRB1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing, 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:DYNLRB1
Gene ID:83658
Uniprot ID:DLRB1_HUMAN
Accession Number:NP_054902
Immunogen:Human
Immunogen Region:1-96aa
Immunogen Sequence:MAEVEETLKR LQSQKGVQGI IVVNTEGIPI KSTMDNPTTT QYASLMHSFI LKARSTVRDI DPQNDLTFLR IRSKKNEIMV APDKDYFLIV IQNPTE
Tissue Specificity High expression in heart, liver, brain and pancreas.moderate in placenta, skeletal muscle and kidney.low in lung, prostate, testis, small intestine and colon. Isoform 1 expression is up-regulated in 64% hepatocellular carcinoma (HCC) patients.
Function Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
Protein Name Dynein Light Chain Roadblock-Type 1
Bithoraxoid-Like Protein
Blp
Dynein Light Chain 2a - Cytoplasmic
Dynein-Associated Protein Km23
Roadblock Domain-Containing Protein 1
Database Links Reactome: R-HSA-5620924
Cellular Localisation Cytoplasm
Cytoskeleton
Alternative Protein Names Dynein Light Chain Roadblock-Type 1 protein
Bithoraxoid-Like Protein protein
Blp protein
Dynein Light Chain 2a - Cytoplasmic protein
Dynein-Associated Protein Km23 protein
Roadblock Domain-Containing Protein 1 protein
DYNLRB1 protein
BITH protein
DNCL2A protein
DNLC2A protein
ROBLD1 protein
HSPC162 protein

Information sourced from Uniprot.org

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