Human DPY30 protein (Recombinant) (His-Tag) (STJP018893)

SKU:
STJP018893
£134.50 - £738.50
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Short Description :Recombinant-Human DPY30-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% Glycerol, 2mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:DPY30
Gene ID:84661
Uniprot ID:DPY30_HUMAN
Accession Number:NP_115963
Immunogen:Human
Immunogen Region:1-99aa
Immunogen Sequence:MEPEQML EGQTQVAENP HSEYGLTDNV ERIVENEKIN AEKSSKQKVD LQSLPTRAYL DQTVVPILLQ GLAVLAKERP PNPIEFLASY LLKNKAQFED RN
Function As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport.
Protein Name Protein Dpy-30 Homolog
Dpy-30-Like Protein
Dpy-30l
Database Links Reactome: R-HSA-3214841
Reactome: R-HSA-5617472
Reactome: R-HSA-8936459
Reactome: R-HSA-9772755
Reactome: R-HSA-9818564
Reactome: R-HSA-9841922
Cellular Localisation Nucleus
Golgi Apparatus
Trans-Golgi Network
Associated With Chromatin At Regions Enriched In Histone H3 Trimethylated At 'Lys-4
Highly Enriched In Gene Promoter Regions And 5' Utrs
But Not In Downstream Regions Of Genes Or 3' Utrs
Alternative Protein Names Protein Dpy-30 Homolog protein
Dpy-30-Like Protein protein
Dpy-30l protein
DPY30 protein

Information sourced from Uniprot.org