Human DOCK4 (Dedicator Of Cytokinesis 4) Sandwich ELISA Kit (STJE0008487)
SPECIFICATIONS
General Information
| Short Description | This DOCK4 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.063ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | DOCK4 |
| Gene ID | 9732 |
| Uniprot ID | DOCK4_HUMAN |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Widely expressed at low level. Highly expressed in skeletal muscle, prostate and ovary. Isoform 2: May be specifically expressed in the brain and eye. |
| Post Translational Modifications | |
| Function | Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form. Involved in regulation of adherens junction between cells. Plays a role in cell migration. Isoform 2: Has a higher guanine nucleotide exchange factor activity compared to other isoforms. |
| Protein Name | Dedicator Of Cytokinesis Protein 4 |
| Database Links | Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013408Reactome: R-HSA-983231 |
| Cellular Localisation | Cell MembraneCell ProjectionCytoplasmCytosolColocalizes With Epha2Rhog And Cttn/Cortactin At The Tip Of Protrusions In Migrating Cells |
| Alternative ELISA Names | Dedicator Of Cytokinesis Protein 4 ELISA kitDOCK4 ELISA kitKIAA0716 ELISA kit |
| output |
Information sourced from Uniprot.org