Human DOCK4 (Dedicator Of Cytokinesis 4) Sandwich ELISA Kit Kit (STJE0008487)

Human DOCK4 (Dedicator Of Cytokinesis 4) Sandwich ELISA Kit Kit (STJE0008487)

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STJE0008487
£465.50 - £636.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.063ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This DOCK4 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: DOCK4
Gene ID: 9732
Uniprot ID: DOCK4_HUMAN
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Widely expressed at low level. Highly expressed in skeletal muscle, prostate and ovary. Isoform 2: May be specifically expressed in the brain and eye.
Post Translational Modifications
Function Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form. Involved in regulation of adherens junction between cells. Plays a role in cell migration. Isoform 2: Has a higher guanine nucleotide exchange factor activity compared to other isoforms.
Protein Name Dedicator Of Cytokinesis Protein 4
Database Links Reactome: R-HSA-9013149
Reactome: R-HSA-9013404
Reactome: R-HSA-9013408
Reactome: R-HSA-983231
Cellular Localisation Cell Membrane
Cell Projection
Cytoplasm
Cytosol
Colocalizes With Epha2
Rhog And Cttn/Cortactin At The Tip Of Protrusions In Migrating Cells
Alternative ELISA Names Dedicator Of Cytokinesis Protein 4 ELISA kit
DOCK4 ELISA kit
KIAA0716 ELISA kit
output

Information sourced from Uniprot.org

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