Human DNAJC24 protein (Recombinant) (His-Tag) (STJP018218)

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STJP018218
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Short Description :Recombinant-Human DNAJC24-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:DNAJC24
Gene ID:120526
Uniprot ID:DJC24_HUMAN
Accession Number:NP_859057
Immunogen:Human
Immunogen Region:1-149aa
Immunogen Sequence:MMAVEQM PKKDWYSILG ADPSANISDL KQKYQKLILM YHPDKQSTDV PAGTVEECVQ KFIEIDQAWK ILGNEETKRE YDLQRCEDDL RNVGPVDAQV YLEEMSWNEG DHSFYLSCRC GGKYSVSKDE AEEVSLISCD TCSLIIELLH YN
Function Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron-bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).
Protein Name Dnaj Homolog Subfamily C Member 24
Csl-Type Zinc Finger-Containing Protein 3
Diphthamide Biosynthesis Protein 4
Database Links Reactome: R-HSA-5358493
Cellular Localisation Cytoplasm
Cytoskeleton
Alternative Protein Names Dnaj Homolog Subfamily C Member 24 protein
Csl-Type Zinc Finger-Containing Protein 3 protein
Diphthamide Biosynthesis Protein 4 protein
DNAJC24 protein
DPH4 protein
ZCSL3 protein

Information sourced from Uniprot.org

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