Name: Human DNAJB9 protein (Recombinant) (N-His) (STJP007771)
SKU: STJP007771
Availability: InStock

Human DNAJB9 protein (Recombinant) (N-His) (STJP007771)

SKU:

STJP007771

$443.48 - $1,940.63

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human DNAJB9-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins. In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1. Also involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Required for survival of B-cell progenitors and normal antibody production.
Protein Name	Dnaj Homolog Subfamily B Member 9 Endoplasmic Reticulum Dna J Domain-Containing Protein 4 Er-Resident Protein Erdj4 Erdj4 Microvascular Endothelial Differentiation Gene 1 Protein Mdg-1
Database Links	Reactome: R-HSA-381038
Cellular Localisation	Endoplasmic Reticulum Lumen
Alternative Protein Names	Dnaj Homolog Subfamily B Member 9 protein Endoplasmic Reticulum Dna J Domain-Containing Protein 4 protein Er-Resident Protein Erdj4 protein Erdj4 protein Microvascular Endothelial Differentiation Gene 1 Protein protein Mdg-1 protein DNAJB9 protein MDG1 protein UNQ743 protein PRO1471 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E. coli
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E. coli
STJP003417	Human TNFSF15 protein (Recombinant) (N-His) (STJP003417)	E. coli
STJP011674	Human MZF1 protein (Recombinant) (N-His) (STJP011674)	E. coli
STJP011681	Human PSME3 protein (Recombinant) (N-His) (STJP011681)	E. coli

Human DNAJB9 protein (Recombinant) (N-His) (STJP007771)

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