| Tissue Specificity | Expressed in a number of tissues. Abundant in testis. |
| Function | DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Also has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. |
| Protein Name | Dna Polymerase LambdaPol LambdaDna Polymerase Beta-2Pol Beta2Dna Polymerase Kappa |
| Database Links | Reactome: R-HSA-5693571 |
| Cellular Localisation | NucleusChromosomeAccumulates At Sites Of Dna Damage |
| Alternative Protein Names | Dna Polymerase Lambda proteinPol Lambda proteinDna Polymerase Beta-2 proteinPol Beta2 proteinDna Polymerase Kappa proteinPOLL protein |
Information sourced from Uniprot.org