Human DHCR24 protein (Recombinant) (N-His) (STJP005447)

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STJP005447
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human DHCR24-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: DHCR24
Gene ID: 1718
Uniprot ID: DHC24_HUMAN
Immunogen Region: Arg53-His516
Immunogen: Homo sapiens (Human)
Function Catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. In addition to its cholesterol-synthesizing activity, can protect cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis.
Protein Name Delta(24-Sterol Reductase
24-Dehydrocholesterol Reductase
3-Beta-Hydroxysterol Delta-24-Reductase
Diminuto/Dwarf1 Homolog
Seladin-1
Database Links Reactome: R-HSA-191273
Reactome: R-HSA-6807047
Reactome: R-HSA-6807062
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Membrane Protein
Golgi Apparatus Membrane
Alternative Protein Names Delta(24-Sterol Reductase protein
24-Dehydrocholesterol Reductase protein
3-Beta-Hydroxysterol Delta-24-Reductase protein
Diminuto/Dwarf1 Homolog protein
Seladin-1 protein
DHCR24 protein
KIAA0018 protein

Information sourced from Uniprot.org

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