Human DEGS1 protein (Recombinant) (N-GST & C-His) (STJP010642)

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STJP010642
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human DEGS1-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: DEGS1
Gene ID: 8560
Uniprot ID: DEGS1_HUMAN
Immunogen Region: Ile230-Glu323
Immunogen: Homo sapiens (Human)
Post Translational Modifications Myristoylation can target the enzyme to the mitochondria leading to an increase in ceramide levels.
Function Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). Catalyzes the equilibrium isomerization of retinols.
Protein Name Sphingolipid Delta(4-Desaturase Des1
Cell Migration-Inducing Gene 15 Protein
Degenerative Spermatocyte Homolog 1
Dihydroceramide Desaturase-1
Membrane Lipid Desaturase
Retinol Isomerase
Database Links Reactome: R-HSA-1660661
Reactome: R-HSA-6798695
Cellular Localisation Mitochondrion Membrane
Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Sphingolipid Delta(4-Desaturase Des1 protein
Cell Migration-Inducing Gene 15 Protein protein
Degenerative Spermatocyte Homolog 1 protein
Dihydroceramide Desaturase-1 protein
Membrane Lipid Desaturase protein
Retinol Isomerase protein
DEGS1 protein
DES1 protein
MLD protein
MIG15 protein

Information sourced from Uniprot.org

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