Human DARS protein (Recombinant) (His-Tag) (STJP017577)

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STJP017577
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human DARS-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 40% Glycerol, 0.15M NaCl, 1mM DTT
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: DARS1
Gene ID: 1615
Uniprot ID: SYDC_HUMAN
Immunogen Region: 1-501aa
Accession Number: NP_001340
Immunogen: Human
Immunogen Sequence: MPSASASRKS QEKPREIMDA AEDYAKERYG ISSMIQSQEK PDRVLVRVRD LTIQKADEVV WVRARVHTSR AKGKQCFLVL RQQQFNVQAL VAVGDHASKQ MVKFAANINK ESIVDVEGVV RKVNQKIGSC TQQDVELHVQ KIYVISLAEP RLPLQLDDAV RPEAEGEEEG RATVNQDTRL DNRVIDLRTS TSQAVFRLQS GICHLF
Tissue Specificity Expression in the developing and adult brain shows similar patterns. Highly expressed in the ventricular and subventricular zones, including hippocampal subfields, the midlateral temporal cortex and the frontal polar cortex. The cerebellum, cerebral cortex, hippocampus, and lateral ventricle show preferential neuronal expression. Expression in the peripheral neurons is evident in the colon.
Function Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.
Protein Name Aspartate--Trna Ligase - Cytoplasmic
Aspartyl-Trna Synthetase
Asprs
Cell Proliferation-Inducing Gene 40 Protein
Database Links Reactome: R-HSA-2408522
Reactome: R-HSA-379716
Reactome: R-HSA-9856649
Cellular Localisation Cytoplasm
Cytosol
Alternative Protein Names Aspartate--Trna Ligase - Cytoplasmic protein
Aspartyl-Trna Synthetase protein
Asprs protein
Cell Proliferation-Inducing Gene 40 Protein protein
DARS1 protein
DARS protein
PIG40 protein

Information sourced from Uniprot.org

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