Human CYTH2 protein (Recombinant) (His-Tag) (STJP017860)

SKU:
STJP017860
$185.61 - $1,019.13
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CYTH2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 10% Glycerol, 1mM DTT
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: CYTH2
Gene ID: 9266
Uniprot ID: CYH2_HUMAN
Immunogen Region: 1-399aa
Accession Number: NP_004219
Immunogen: Human
Immunogen Sequence: MGSSHHHHHH SSGLVPRGSH MGSMEDGVYE PPDLTPEERM ELENIRRRKQ ELLVEIQRLR EELSEAMSEV EGLEANEGSK TLQRNRKMAM GRKKFNMDPK KGIQFLVENE LLQNTPEEIA RFLYKGEGLN KTAIGDYLGE REELNLAVLH AFVDLHEFTD LNLVQALRQF LWSFRLPGEA QKIDRMMEAF AQRYCLCNPG VFQSTDTCYV LSFAVIMLNT SLHNPNVR
Tissue Specificity Widely expressed.
Function Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Activates ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane. Involved in neurite growth.
Protein Name Cytohesin-2
Arf Exchange Factor
Arf Nucleotide-Binding Site Opener
Protein Arno
Ph - Sec7 And Coiled-Coil Domain-Containing Protein 2
Database Links Reactome: R-HSA-6811438
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Cytoplasm
Cell Projection
Growth Cone
Cell Junction
Tight Junction
Adherens Junction
Both Isoform 1 And Isoform 2 Are Recruited To The Cell Membrane Through Its Association With Arl4a
Arl4c And Arl4d
They Require Also Interaction With Phosphoinositides For Targeting To Plasma Membrane
In Differentiating Neuroblastoma Cells
Colocalizes With Ccdc120 In Both Neurite Shaft And Growth Cone Areas
Alternative Protein Names Cytohesin-2 protein
Arf Exchange Factor protein
Arf Nucleotide-Binding Site Opener protein
Protein Arno protein
Ph - Sec7 And Coiled-Coil Domain-Containing Protein 2 protein
CYTH2 protein
ARNO protein
PSCD2 protein
PSCD2L protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP005876 Human CYTH2 protein (Recombinant) (N-His) (STJP005876) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJP016456 Human PINX1 protein (Recombinant) (His-Tag) (STJP016456) E.coli SDS-PAGE
STJP016475 Human WWOX protein (Recombinant) (His-Tag) (STJP016475) E.coli SDS-PAGE
STJP016472 Human CITED2 protein (Recombinant) (His-Tag) (STJP016472) E.coli SDS-PAGE
STJP016506 Human SAT1 protein (Recombinant) (His-Tag) (STJP016506) E.coli SDS-PAGE

Related Products

!