Human CXCL1/GRO-alpha protein (Recombinant) (No-tag NA) (STJP001996)

SKU:
STJP001996
£104.50 - £347.50
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Short Description :Recombinant-Human CXCL1/GRO-alpha-No-tag protein was developed in e.coli using the region Ala35-As n107. For use in research applications.
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Formulation:Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:<0.1 EU/Mu g of the protein by LAL method.
Gene Symbol:CXCL1
Gene ID:2919
Uniprot ID:GROA_HUMAN
Immunogen:Recombinant Human CX CL1/GRO-alpha Protei n is produced by E. coli expression syst em. The target prote in is expressed with sequence ( Ala35-As n107) of Human CXCL1/GRO-alpha (Accessio n #NP_001502.1) fuse d with No-tag.
Immunogen Region:Ala35-As n107
Immunogen Sequence:ASVATELRCQCLQTLQGIHP KNIQSVNVKSPGPHCAQTEV IATLKNGRKACLNPASPIVK KIIEKMLNSDKSN
Function Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.
Protein Name Growth-Regulated Alpha Protein
C-X-C Motif Chemokine 1
Gro-Alpha(1-73
Melanoma Growth Stimulatory Activity
Mgsa
Neutrophil-Activating Protein 3
Nap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Reactome: R-HSA-6783783
Reactome: R-HSA-6798695
Cellular Localisation Secreted
Alternative Protein Names Growth-Regulated Alpha Protein protein
C-X-C Motif Chemokine 1 protein
Gro-Alpha(1-73 protein
Melanoma Growth Stimulatory Activity protein
Mgsa protein
Neutrophil-Activating Protein 3 protein
Nap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 protein
CXCL1 protein
GRO protein
GRO1 protein
GROA protein
MGSA protein
SCYB1 protein

Information sourced from Uniprot.org