Human Crystallin zeta/CRYZ protein (Recombinant) (His-Tag) (STJP018846)

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STJP018846
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Short Description :Recombinant-Human Crystallin zeta/CRYZ-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% Glycerol, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:CRYZ
Gene ID:1429
Uniprot ID:QOR_HUMAN
Accession Number:NP_001123514
Immunogen:Human
Immunogen Region:1-329aa
Immunogen Sequence:MATGQKL MRAVRVFEFG GPEVLKLRSD IAVPIPKDHQ VLIKVHACGV NPVETYIRSG TYSRKPLLPY TPGSDVAGVI EAVGDNASAF KKGDRVFTSS TISGGYAEYA LAADHTVYKL PEKLDFKQGA AIGIPYFTAY RALIHSACVK AGESVLVHGA SGGVGLAACQ IARAYGLKIL GTAGTEEGQK IVLQNGAHEV FNHREV
Tissue Specificity Only very low amounts in the lens.
Function Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding.
Protein Name Quinone Oxidoreductase
Nadph -Quinone Reductase
Zeta-Crystallin
Database Links
Cellular Localisation Cytoplasm
Alternative Protein Names Quinone Oxidoreductase protein
Nadph -Quinone Reductase protein
Zeta-Crystallin protein
CRYZ protein

Information sourced from Uniprot.org

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