Human CREBZF protein (Recombinant) (His-Tag) (STJP018908)

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STJP018908
£134.50 - £738.50
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CREBZF-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in phosphate-Buffered Saline (pH 7.4) containing 20% Glycerol, 1mM DTT, 0.1mM PMSF
Concentration: 0.25 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: CREBZF
Gene ID: 58487
Uniprot ID: ZHANG_HUMAN
Immunogen Region: 1-354aa
Accession Number: NP_001034707
Immunogen: Human
Immunogen Sequence: MGSSHHHHHH SSGLVPRGSH MGSMRHSLTK LLAASGSNSP TRSESPEPAA TCSLPSDLTR AAAGEEETAA AGSPGRKQQF GDEGELEAGR GSRGGVAVRA PSPEEMEEEA IASLPGEETE DMDFLSGLEL ADLLDPRQPD WHLDPGLSSP GPLSSSGGGS DSGGLWRGDD DDEAAAAEMQ RFSDLLQRLL NGIGGCSSSS DSGSAEKRRR KSPGGGGGGG SGNDNNQA
Tissue Specificity In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lung. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver.
Function Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.
Protein Name Creb/Atf Bzip Transcription Factor
Host Cell Factor-Binding Transcription Factor Zhangfei
Hcf-Binding Transcription Factor Zhangfei
Database Links
Cellular Localisation Nucleus
Colocalizes In Promyelocytic Leukemia Protein Nuclear Bodies (Pml-Nb) With Creb3 And Hcfc1
Alternative Protein Names Creb/Atf Bzip Transcription Factor protein
Host Cell Factor-Binding Transcription Factor Zhangfei protein
Hcf-Binding Transcription Factor Zhangfei protein
CREBZF protein
ZF protein

Information sourced from Uniprot.org

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