Human CMBL protein (Recombinant) (His-Tag) (STJP017757)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CMBL-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% Glycerol, 1mM EDTA |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CMBL |
| Gene ID | 134147 |
| Uniprot ID | CMBL_HUMAN |
| Accession Number | NP_620164.1 |
| Immunogen | Human |
| Immunogen Region | 1-245aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Widely expressed, with highest levels in liver, followed by kidney, small intestine and colon. Present in liver and intestine (at protein level). |
| Function | Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin. |
| Protein Name | Carboxymethylenebutenolidase Homolog |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Protein Names | Carboxymethylenebutenolidase Homolog proteinCMBL protein |
Information sourced from Uniprot.org