Human CLIC3 protein (Recombinant) (N-His) (STJP016363)

SKU:
STJP016363
£208.50 - £1,163.50
Free Shipping
Processing The item has been added

Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CLIC3-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: Please contact us for further information.
Gene Symbol: CLIC3
Gene ID: 9022
Uniprot ID: CLIC3_HUMAN
Immunogen Region: Asp45-Arg236
Immunogen: Homo sapiens (Human)
Function In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Reduced in a glutathione-dependent way and secreted into the extracellular matrix where it activates TGM2 and promotes blood vessel growth during tissue remodeling as occurs in tumorigenesis. Can reduce specific cysteines in TGM2 and regulate cofactor binding. Can insert into membranes and form outwardly rectifying chloride ion channels. May participate in cellular growth control.
Protein Name Chloride Intracellular Channel Protein 3
Glutaredoxin-Like Oxidoreductase Clic3
Database Links
Cellular Localisation Nucleus
Membrane
Single-Pass Membrane Protein
Cell Membrane
Cytoplasm
Secreted
Extracellular Space
Extracellular Matrix
Predominantly Nuclear
Some Protein Was Found In The Cytoplasm
Exists Both As Soluble Cytoplasmic Protein And As Membrane Protein With Probably A Single Transmembrane Domain
Secreted Into The Extracellular Matrix By Activated Fibroblasts
Alternative Protein Names Chloride Intracellular Channel Protein 3 protein
Glutaredoxin-Like Oxidoreductase Clic3 protein
CLIC3 protein

Information sourced from Uniprot.org