Human CLCN6 protein (Recombinant) (N-His) (STJP015790)

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STJP015790
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Short Description :Recombinant-Human CLCN6-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:Please contact us for further information.
Gene Symbol:CLCN6
Gene ID:1185
Uniprot ID:CLCN6_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Glu593-Ile869
Post Translational Modifications N-glycosylated on several asparagine residues.
Function Voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the late endosome lumen. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters.
Protein Name H(+/Cl(- Exchange Transporter 6
Chloride Channel Protein 6
Clc-6
Chloride Transport Protein 6
Database Links Reactome: R-HSA-2672351
Reactome: R-HSA-6802952
Cellular Localisation Late Endosome Membrane
Multi-Pass Membrane Protein
Alternative Protein Names H(+/Cl(- Exchange Transporter 6 protein
Chloride Channel Protein 6 protein
Clc-6 protein
Chloride Transport Protein 6 protein
CLCN6 protein
KIAA0046 protein

Information sourced from Uniprot.org

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