Human CHRNa1 (Cholinergic Receptor, Nicotinic, Alpha 1) Sandwich ELISA Kit Kit (STJE0007939)

SKU:
STJE0007939
£428.50 - £585.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.28ng/mL
Detection Limit: 0.781-50ng/mL
Short Description : This CHRNa1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: CHRNA1
Gene ID: 1134
Uniprot ID: ACHA_HUMAN
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Isoform 1 is only expressed in skeletal muscle. Isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus.
Post Translational Modifications
Function Isoform 1: Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Isoform 2: Non functional acetylcholine receptor alpha subunit which is not integrated into functional acetylcholine-gated cation-selective channels.
Protein Name Acetylcholine Receptor Subunit Alpha
Database Links Reactome: R-HSA-629594
Reactome: R-HSA-629597
Cellular Localisation Postsynaptic Cell Membrane
Multi-Pass Membrane Protein
Cell Membrane
Alternative ELISA Names Acetylcholine Receptor Subunit Alpha ELISA kit
CHRNA1 ELISA kit
ACHRA ELISA kit
CHNRA ELISA kit
output

Information sourced from Uniprot.org