| Tissue Specificity | Isoform 1 is only expressed in skeletal muscle. Isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus. |
| Post Translational Modifications | |
| Function | Isoform 1: Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Isoform 2: Non functional acetylcholine receptor alpha subunit which is not integrated into functional acetylcholine-gated cation-selective channels. |
| Protein Name | Acetylcholine Receptor Subunit Alpha |
| Database Links | Reactome: R-HSA-629594Reactome: R-HSA-629597 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative ELISA Names | Acetylcholine Receptor Subunit Alpha ELISA kitCHRNA1 ELISA kitACHRA ELISA kitCHNRA ELISA kit |
| output | |
Information sourced from Uniprot.org
