Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human CEACAM8/CD66b-C-hFC protein was developed from hek293 cells and has a target region of C-hFC. For use in research applications. |
Formulation: |
Lyophilized from a 0.2 Mu m filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CEACAM8 |
Gene ID: |
1088 |
Uniprot ID: |
CEAM8_HUMAN |
Immunogen Region: |
Gln35-Ser319 |
Immunogen: |
Recombinant Human CEACAM8/CD66b Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Gln35-Ser319) of human CEACAM8 (Accession #P31997) fused with a hFC tag at the C-terminus. |
Post Translational Modifications | Glycosylated. |
Function | Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. |
Protein Name | Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8Cd67 AntigenCarcinoembryonic Antigen Cgm6Non-Specific Cross-Reacting Antigen Nca-95Cd Antigen Cd66b |
Database Links | Reactome: R-HSA-1566977Reactome: R-HSA-202733Reactome: R-HSA-6798695 |
Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorCell Surface |
Alternative Protein Names | Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 proteinCd67 Antigen proteinCarcinoembryonic Antigen Cgm6 proteinNon-Specific Cross-Reacting Antigen Nca-95 proteinCd Antigen Cd66b proteinCEACAM8 proteinCGM6 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance