Human CD66c/CEACAM6 protein (Recombinant) (C-His) (STJP004675)

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STJP004675
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD66c/CEACAM6-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CEACAM6
Gene ID: 4680
Uniprot ID: CEAM6_HUMAN
Immunogen Region: Met1-Gly320
Immunogen: Homo sapiens (Human)
Post Translational Modifications Glycosylated.
Function Cell surface glycoprotein that plays a role in cell adhesion and tumor progression. Intercellular adhesion occurs in a calcium- and fibronectin-independent manner. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. Plays a role in neutrophil adhesion to cytokine-activated endothelial cells. Plays a role in cell migration and cell adhesion to endothelial cells.
Protein Name Cell Adhesion Molecule Ceacam6
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6
Cea Cell Adhesion Molecule 6
Non-Specific Crossreacting Antigen
Normal Cross-Reacting Antigen
Cd Antigen Cd66c
Database Links Reactome: R-HSA-1566977
Reactome: R-HSA-202733
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Apical Cell Membrane
Cell Surface
Localized To The Apical Glycocalyx Surface
Alternative Protein Names Cell Adhesion Molecule Ceacam6 protein
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 protein
Cea Cell Adhesion Molecule 6 protein
Non-Specific Crossreacting Antigen protein
Normal Cross-Reacting Antigen protein
Cd Antigen Cd66c protein
CEACAM6 protein
NCA protein

Information sourced from Uniprot.org

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