Human CD64/FCGR1A protein (Recombinant-Active) (C-His) (STJP012463)

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STJP012463-100
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Host: Mammalian Cells
Applications: ELISA/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human CD64/FCGR1A-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: < 1 EU/µg as determined by LAL test.
Gene Symbol: FCGR1A
Gene ID: 2209
Uniprot ID: FCGR1_HUMAN
Immunogen Region: Gln16-Pro288
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated on serine residues.
Function High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells.
Protein Name High Affinity Immunoglobulin Gamma Fc Receptor I
Igg Fc Receptor I
Fc-Gamma Ri
Fcri
Fc-Gamma Ria
Fcgammaria
Cd Antigen Cd64
Database Links Reactome: R-HSA-1236978
Reactome: R-HSA-198933
Reactome: R-HSA-2029481
Reactome: R-HSA-2029482
Reactome: R-HSA-2029485
Reactome: R-HSA-877300
Reactome: R-HSA-9664323
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Stabilized At The Cell Membrane Through Interaction With Fcer1g
Alternative Protein Names High Affinity Immunoglobulin Gamma Fc Receptor I protein
Igg Fc Receptor I protein
Fc-Gamma Ri protein
Fcri protein
Fc-Gamma Ria protein
Fcgammaria protein
Cd Antigen Cd64 protein
FCGR1A protein
FCG1 protein
FCGR1 protein
IGFR1 protein

Information sourced from Uniprot.org

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