Human CD58/LFA-3 protein (Recombinant) (His-Tag) (STJP018995)

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STJP018995
£134.50 - £738.50
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Host: E.coli
Applications: SDS-PAGE/Denatured
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD58/LFA-3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: CD58
Gene ID: 965
Uniprot ID: LFA3_HUMAN
Immunogen Region: 29-215aa
Accession Number: NP_001770
Immunogen: Human
Immunogen Sequence: FSQQIYG VVYGNVTFHV PSNVPLKEVL WKKQKDKVAE LENSEFRAFS SFKNRVYLDT VSGSLTIYNL TSSDEDEYEM ESPNITDTMK FFLYVLESLP SPTLTCALTN GSIEVQCMIP EHYNSHRGLI MYSWDCPMEQ CKRNSTSIYF KMENDLPQKI QCTLSNPLFN TTSSIILTTC IPSSGHSRHR
Function Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Protein Name Lymphocyte Function-Associated Antigen 3
Ag3
Surface Glycoprotein Lfa-3
Cd Antigen Cd58
Database Links Reactome: R-HSA-202733
Reactome: R-HSA-6798695
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Lymphocyte Function-Associated Antigen 3 protein
Ag3 protein
Surface Glycoprotein Lfa-3 protein
Cd Antigen Cd58 protein
CD58 protein
LFA3 protein

Information sourced from Uniprot.org

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