Name: Human CD48 protein (Recombinant) (C-Fc) (STJP003892)
SKU: STJP003892
Availability: InStock

Human CD48 protein (Recombinant) (C-Fc) (STJP003892)

SKU:

STJP003892

£267.50 - £2,006.50

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Short Description :	Recombinant-Human CD48-C-Fc protein was developed from mammalian cells for the region C-Fc. For use in research applications.
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Host:	Mammalian Cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range:	Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including CD244/2B4 or CD2 to regulate immune cell function and activation. Participates in T-cell signaling transduction by associating with CD2 and efficiently bringing the Src family protein kinase LCK and LAT to the TCR/CD3 complex. In turn, promotes LCK phosphorylation and subsequent activation. Induces the phosphorylation of the cytoplasmic immunoreceptortyrosine switch motifs (ITSMs) of CD244 initiating a series of signaling events that leads to the generation of the immunological synapse and the directed release of cytolytic granules containing perforin and granzymes by T-lymphocytes and NK-cells.
Protein Name	Cd48 Antigen B-Lymphocyte Activation Marker Blast-1 Bcm1 Surface Antigen Leukocyte Antigen Mem-102 Slam Family Member 2 Slamf2 Signaling Lymphocytic Activation Molecule 2 Tct.1 Cd Antigen Cd48
Database Links	Reactome: R-HSA-202733
Cellular Localisation	Cell Membrane Lipid-Anchor Gpi-Anchor Membrane Raft Secreted
Alternative Protein Names	Cd48 Antigen protein B-Lymphocyte Activation Marker Blast-1 protein Bcm1 Surface Antigen protein Leukocyte Antigen Mem-102 protein Slam Family Member 2 protein Slamf2 protein Signaling Lymphocytic Activation Molecule 2 protein Tct.1 protein Cd Antigen Cd48 protein CD48 protein BCM1 protein BLAST1 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP013144	Human CD48 protein (Recombinant) (C-Fc-His) (STJP013144)	Mammalian Cells	ELISA/WB
STJP013145	Human CD48 protein (Recombinant) (C-mFc) (STJP013145)	Mammalian Cells	ELISA/WB
STJP008650	Human CD48 protein (Recombinant) (C-His) (STJP008650)	Mammalian Cells	ELISA/Immunogen/SDS-PAGE/WB
STJP011834	Human CD48 protein (Recombinant-Active) (C-His) (STJP011834)	Mammalian Cells	ELISA/WB
STJP001035	Human SLAMF2/CD48 protein (Recombinant) (C-His) (STJP001035)	HEK293 cells

Human CD48 protein (Recombinant) (C-Fc) (STJP003892)

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