Name: Human CD48 protein (Recombinant-Active) (C-His) (STJP011834)
SKU: STJP011834-100
Price: 503.5 GBP
Availability: InStock

Human CD48 protein (Recombinant-Active) (C-His) (STJP011834)

SKU:

STJP011834-100

£503.50

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Short Description :	Recombinant-Active-Human CD48-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications:	ELISA/WB
Host:	Mammalian Cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation:	Unconjugated
Dilution Range:	Reconstitute in sterile water for a stock solution.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:	<1 EU/Mu g of the protein by the LAL method.
Immunoreactivity:	Immobilised recombinant human CD48 at 5 Mu g/mL (100 Mu L/well) can bind recombinant human CD244 with a linear range of 0.2-1 Mu g/mL.

Function	Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including CD244/2B4 or CD2 to regulate immune cell function and activation. Participates in T-cell signaling transduction by associating with CD2 and efficiently bringing the Src family protein kinase LCK and LAT to the TCR/CD3 complex. In turn, promotes LCK phosphorylation and subsequent activation. Induces the phosphorylation of the cytoplasmic immunoreceptortyrosine switch motifs (ITSMs) of CD244 initiating a series of signaling events that leads to the generation of the immunological synapse and the directed release of cytolytic granules containing perforin and granzymes by T-lymphocytes and NK-cells.
Protein Name	Cd48 Antigen B-Lymphocyte Activation Marker Blast-1 Bcm1 Surface Antigen Leukocyte Antigen Mem-102 Slam Family Member 2 Slamf2 Signaling Lymphocytic Activation Molecule 2 Tct.1 Cd Antigen Cd48
Database Links	Reactome: R-HSA-202733
Cellular Localisation	Cell Membrane Lipid-Anchor Gpi-Anchor Membrane Raft Secreted
Alternative Protein Names	Cd48 Antigen protein B-Lymphocyte Activation Marker Blast-1 protein Bcm1 Surface Antigen protein Leukocyte Antigen Mem-102 protein Slam Family Member 2 protein Slamf2 protein Signaling Lymphocytic Activation Molecule 2 protein Tct.1 protein Cd Antigen Cd48 protein CD48 protein BCM1 protein BLAST1 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP008650	Human CD48 protein (Recombinant) (C-His) (STJP008650)	Mammalian Cells	ELISA/Immunogen/SDS-PAGE/WB
STJP013144	Human CD48 protein (Recombinant) (C-Fc-His) (STJP013144)	Mammalian Cells	ELISA/WB
STJP001035	Human SLAMF2/CD48 protein (Recombinant) (C-His) (STJP001035)	HEK293 cells
STJP000883	Human SLAMF2/CD48 protein (Recombinant) (C-hFc&His) (STJP000883)	HEK293 cells
STJP003891	Human CD48 protein (Recombinant) (N-His) (STJP003891)	E.coli	ELISA/Immunogen/SDS-PAGE/WB

Human CD48 protein (Recombinant-Active) (C-His) (STJP011834)

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