Human CD370/CLEC9A protein (Recombinant) (N-Fc) (STJP007154)

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STJP007154
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD370/CLEC9A-N-Fc protein was developed from mammalian cells and has a target region of N-Fc. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CLEC9A
Gene ID: 283420
Uniprot ID: CLC9A_HUMAN
Immunogen Region: Lys57-Val241
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated.
Function Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.
Protein Name C-Type Lectin Domain Family 9 Member A
Cd Antigen Cd370
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names C-Type Lectin Domain Family 9 Member A protein
Cd Antigen Cd370 protein
CLEC9A protein
UNQ9341 protein
PRO34046 protein

Information sourced from Uniprot.org

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