Human CD307a/FCRL1 protein (Recombinant) (C-His) (STJP007126)

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STJP007126
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD307a/FCRL1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: FCRL1
Gene ID: 115350
Uniprot ID: FCRL1_HUMAN
Immunogen Region: Met1-Asn303
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated on tyrosines upon activation.
Function Type I transmembrane surface glycoprotein preferentially expressed by B-cells that regulates BCR-mediated signaling responses. Recruits ABL1 as the intracellular effector molecule to enhance B-cell activation. Plays also a negative role by suppressing ERK activation under homeostatic and BCR-stimulated conditions in a GRB2-dependent manner.
Protein Name Fc Receptor-Like Protein 1
Fcr-Like Protein 1
Fcrl1
Fc Receptor Homolog 1
Fcrh1
Ifgp Family Protein 1
Hifgp1
Immune Receptor Translocation-Associated Protein 5
Cd Antigen Cd307a
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Fc Receptor-Like Protein 1 protein
Fcr-Like Protein 1 protein
Fcrl1 protein
Fc Receptor Homolog 1 protein
Fcrh1 protein
Ifgp Family Protein 1 protein
Hifgp1 protein
Immune Receptor Translocation-Associated Protein 5 protein
Cd Antigen Cd307a protein
FCRL1 protein
FCRH1 protein
IFGP1 protein
IRTA5 protein

Information sourced from Uniprot.org

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