Human CD303/CLEC4C protein (Recombinant) (N-His) (STJP005751)

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STJP005751
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD303/CLEC4C-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CLEC4C
Gene ID: 170482
Uniprot ID: CLC4C_HUMAN
Immunogen Region: Ser67-Ile213
Immunogen: Homo sapiens (Human)
Function Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
Protein Name C-Type Lectin Domain Family 4 Member C
Blood Dendritic Cell Antigen 2
Bdca-2
C-Type Lectin Superfamily Member 7
Dendritic Lectin
Cd Antigen Cd303
Database Links Reactome: R-HSA-5621480
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names C-Type Lectin Domain Family 4 Member C protein
Blood Dendritic Cell Antigen 2 protein
Bdca-2 protein
C-Type Lectin Superfamily Member 7 protein
Dendritic Lectin protein
Cd Antigen Cd303 protein
CLEC4C protein
BDCA2 protein
CLECSF11 protein
CLECSF7 protein
DLEC protein
HECL protein
UNQ9361 protein
PRO34150 protein

Information sourced from Uniprot.org

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