| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1.0 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | CLEC10A |
| Gene ID: | 10462 |
| Uniprot ID: | CLC10_HUMAN |
| Immunogen Region: | Gln61-His316 |
| Immunogen: | Recombinant Human CD301 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln61-His316) of human CLEC10A/MGL1/CD301 (Accession #NP_878910.1) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | QNSKFQRDLVTLRTDFSNFT SNTVAEIQALTSQGSSLEET IASLKAEVEGFKQERQAGVS ELQEHTTQKAHLGHCPHCPS VCVPVHSEMLLRVQQLVQDL KKLTCQVATLNNNASTEGTC CPVNWVEHQDSCYWFSHSGM SWAEAEKYCQLKNAHLVVIN SREEQNFVQKYLGSAYTWMG LSDPEGAWKWVDGTDYATGF QNWKPGQPDDWQGHGLGGGE DCAHFHPDGRWNDDVCQRP |
| Function | Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells. |
| Protein Name | C-Type Lectin Domain Family 10 Member AC-Type Lectin Superfamily Member 14Macrophage Lectin 2Cd Antigen Cd301 |
| Database Links | Reactome: R-HSA-5621480 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | C-Type Lectin Domain Family 10 Member A proteinC-Type Lectin Superfamily Member 14 proteinMacrophage Lectin 2 proteinCd Antigen Cd301 proteinCLEC10A proteinCLECSF13 proteinCLECSF14 proteinHML protein |
Information sourced from Uniprot.org
