Human CD30 (TNFRSF8) protein (Recombinant) (STJP000503)

Name: Human CD30 (TNFRSF8) protein (Recombinant) (STJP000503)
SKU: STJP000503
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostHEK293

ConjugationUnconjugated

ImmunogenOptimized DNA sequence encoding extracellular domain of Human CD30 including a C-terminal His tag was expressed in HEK293 cells. NA

STJP000503

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Short Description	Recombinant-Human CD30 (TNFRSF8)-protein was developed from hek293. For use in research applications.
Host	HEK293
Note	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Formulation	Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose.
Storage Instruction	Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Immunoreactivity	The activity was tested by the ability of immobilized recombinant human CD30 to bind Human CD30 Ligand with a linear range of 6-800 ng/ml NA

Gene Symbol	TNFRSF8
Gene ID	943
Uniprot ID	TNR8_HUMAN
Immunogen	Optimized DNA sequence encoding extracellular domain of Human CD30 including a C-terminal His tag was expressed in HEK293 cells. NA
Immunogen Region	ECD

Tissue Specificity	Isoform 2: Detected in alveolar macrophages (at protein level).
Post Translational Modifications	Phosphorylated on serine and tyrosine residues (Probable). Isoform 2 is constitutively phosphorylated.
Function	Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
Protein Name	Tumor Necrosis Factor Receptor Superfamily Member 8 Cd30l Receptor Ki-1 Antigen Lymphocyte Activation Antigen Cd30 Cd Antigen Cd30
Database Links	Reactome: R-HSA-5669034
Cellular Localisation	Isoform 1: Cell Membrane Single-Pass Type I Membrane Protein Isoform 2: Cytoplasm
Alternative Protein Names	Tumor Necrosis Factor Receptor Superfamily Member 8 protein Cd30l Receptor protein Ki-1 Antigen protein Lymphocyte Activation Antigen Cd30 protein Cd Antigen Cd30 protein TNFRSF8 protein CD30 protein D1S166E protein

Information sourced from Uniprot.org