Human CD264/TNFRSF10D/TRAIL-R4 protein (Recombinant-Active) (C-hFc-His) (STJP012305)

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STJP012305-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human CD264/TNFRSF10D/TRAIL-R4-C-hFc-His protein was developed from mammalian cells and has a target region of C-hFc-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: TNFRSF10D
Gene ID: 8793
Uniprot ID: TR10D_HUMAN
Immunogen Region: Ala56-His211
Immunogen: Homo sapiens (Human)
Function Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. it cannot but it can induce the NF-kappa-B pathway.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 10d
Decoy Receptor 2
Dcr2
Tnf-Related Apoptosis-Inducing Ligand Receptor 4
Trail Receptor 4
Trail-R4
Trail Receptor With A Truncated Death Domain
Cd Antigen Cd264
Database Links Reactome: R-HSA-202733
Reactome: R-HSA-6803211
Reactome: R-HSA-75158
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Tumor Necrosis Factor Receptor Superfamily Member 10d protein
Decoy Receptor 2 protein
Dcr2 protein
Tnf-Related Apoptosis-Inducing Ligand Receptor 4 protein
Trail Receptor 4 protein
Trail-R4 protein
Trail Receptor With A Truncated Death Domain protein
Cd Antigen Cd264 protein
TNFRSF10D protein
DCR2 protein
TRAILR4 protein
TRUNDD protein
UNQ251 protein
PRO288 protein

Information sourced from Uniprot.org

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