Name: Human CD262/TNFRSF10B/DR5 protein (Recombinant) (C-His) (STJP008638)
SKU: STJP008638
Availability: InStock

Human CD262/TNFRSF10B/DR5 protein (Recombinant) (C-His) (STJP008638)

SKU:

STJP008638

$369.15 - $2,768.97

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Short Description :	Recombinant-Human CD262/TNFRSF10B/DR5-C-His protein was developed from mammalian cells for the region C-His. For use in research applications.
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Host:	Mammalian Cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range:	Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Post Translational Modifications	(Microbial infection) Glycosylated on Arg residue by S.typhimurium protein Ssek3.
Function	Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
Protein Name	Tumor Necrosis Factor Receptor Superfamily Member 10b Death Receptor 5 Tnf-Related Apoptosis-Inducing Ligand Receptor 2 Trail Receptor 2 Trail-R2 Cd Antigen Cd262
Database Links	Reactome: R-HSA-140534 Reactome: R-HSA-202733 Reactome: R-HSA-3371378 Reactome: R-HSA-5213460 Reactome: R-HSA-5218900 Reactome: R-HSA-6803211 Reactome: R-HSA-69416 Reactome: R-HSA-75158
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Tumor Necrosis Factor Receptor Superfamily Member 10b protein Death Receptor 5 protein Tnf-Related Apoptosis-Inducing Ligand Receptor 2 protein Trail Receptor 2 protein Trail-R2 protein Cd Antigen Cd262 protein TNFRSF10B protein DR5 protein KILLER protein TRAILR2 protein TRICK2 protein ZTNFR9 protein UNQ160 protein PRO186 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP020120	Human TNFRSF10B/DR5/TRAIL-R2/CD262 protein (Recombinant) (C-His&Avi) {Biotin} (STJP020120)	HEK293 cells
STJP012968	Human CD262/TRAIL-R2/DR5 protein (Recombinant) (C-Fc-His) (STJP012968)	Mammalian Cells	ELISA/WB
STJP012345	Human CD262/TRAIL-R2/DR5 protein (Recombinant-Active) (C-His) (STJP012345)	Mammalian Cells	ELISA/WB
STJP001381	Human TNFRSF10B/DR5/TRAIL-R2 protein (Recombinant) (C-hFc&His) (STJP001381)	HEK293 cells
STJP002613	Human TNFRSF10B/DR5/TRAIL-R/2CD262 protein (Recombinant) (C-His) (STJP002613)	HEK293 cells

Human CD262/TNFRSF10B/DR5 protein (Recombinant) (C-His) (STJP008638)

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